Backup Exchange, SQL, Active Directory with VMWARE

What is the best practice to backup an Exchange server or a SQL or even Domain controller (AD).

Actualy I'm backup them with VMWARE (Flashbackup-Windows) policies.

Someone told me that the Flashbackup-Windows isnt supported by Microsoft for Exchange, SQL etc. and that we should install the NB Agent instead to backup the VMDK (Snaphot) block level.

I'm using Netbackup 7.5.0.5

Thanks